CompletedPhase 4

Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis

Egypt60 participantsStarted 2024-07-01

Plain-language summary

Several studies investigated the effectiveness of Gabapentin in Uremic Pruritus (UP). No previous studies investigated the use of fexofenadine in UP. The aim of this trial is to assess the safety and possible efficacy of fexofenadine in patients with UP.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years old. * ESRD on regular hemodialysis. * Moderate and severe Uremic Pruritus as assessed by Visual Analogue Scale. * Able to provide an informed consent. Exclusion Criteria: * Age \< 18 years old. * Patients not on regular hemodialysis. * Pruritus due to other cause. * Cancer patients. * Pregnancy or breastfeeding. * Patients with history of substance abuse. * Patients with myasthenia gravis. * Patients who refuse or are unable to provide an informed consent.

What they're measuring

The Visual Analogue Scale (VAS)

Timeframe: 3 months

Skindex score

Timeframe: 3 months

Kidney Disease Quality of Life Short Form (KDQOL-SF™)

Timeframe: 3 months

Trial details

NCT IDNCT06466421

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-01

View on ClinicalTrials.gov More Uremic Pruritus trials