HIBOC = Hepatic Imaging Biomarkers in Obese Children (NCT06463223) | Clinical Trial Compass
By InvitationNot Applicable
HIBOC = Hepatic Imaging Biomarkers in Obese Children
Sweden300 participantsStarted 2025-02-01
Plain-language summary
The goal of this prospective, diagnostic observational study is to learn about how imaging based markers for components of liver disease appear in children with obesity. It aims to determine whether the imaging markers (ultrasound and MRI) for liver disease can be tools to improve diagnostics for liver affection in children with obesity and to ascertain how the markers are related to multiple clinical measures, for example BMI and serology measure, and treatment effects over time.
Who can participate
Age range
9 Years – 14 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 9 to 14 years
* New referral/first visit or follow-up annual visit at each healthcare center (Child and adolescent oriented centers) included
* BMI 30 or more
* Obesity \>1 year at inclusion
Exclusion Criteria:
* Difficulty understanding written/oral information
* Comorbidities that can affect the liver (e.g., medications or diseases with known liver impact)
* Claustrophobia (applies to the MRI cohort)
* Implants or other factors that prevent MRI (applies to the MRI cohort)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Attenuation imaging
Timeframe: baseline, 1 year, 2 years and 3 years follow up
2
Shear wave dispersion
Timeframe: baseline, 1 year, 2 years and 3 years follow up
3
shear wave dispersion
Timeframe: baseline, 1 year, 2 years and 3 years follow up