By InvitationNot Applicable

Cold Snare Piecemeal Resection vs Cold Snare Endoscopic Mucosal Resection

United States570 participantsStarted 2024-09-06

Plain-language summary

The study will compare the use of cold snare piecemeal resection (CSPR) vs cold endoscopic mucosal resection (Cold EMR). The study will include two cohorts: one cohort for conventional adenomas 10-19mm in size and one cohort for serrated lesions 10mm or larger.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. ≥ 18 years of age
✓. Presenting for a screening, surveillance, diagnostic, or therapeutic colonoscopy
✓. Found to have:
✓. Ability to provide informed consent

Exclusion criteria

✕. Pedunculated or semi-pedunculated polyps (as defined by Paris Classification type Ip or Isp)
✕. Polyps confirmed to be anything other than:
✕. Patients with Ulcerative Colitis or Crohn's disease
✕. Polyps with features suggestive of submucosal invasion
✕. Polyps that are not able to be removed endoscopically due to location (e.g. extending into appendiceal orifice or diverticulum)
✕. Patients with a known or suspected diagnosis of any of the following polyposis syndromes with known genetic mutations:
✕. Subjects whose colonoscopy procedure is not able to be completed due to bowel prep precluding polyp identification.

What they're measuring

Efficacy of Resection (Central Post-Resection Biopsies)

Timeframe: 1 day

Efficacy of Resection (Peripheral Post-Resection Biopsies)

Timeframe: 1 day

Trial details

NCT IDNCT06462521

SponsorIndiana University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-07

View on ClinicalTrials.gov More Colon Cancer trials