Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Pre… (NCT06458530) | Clinical Trial Compass
CompletedNot Applicable
Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.
United States74 participantsStarted 2024-07-09
Plain-language summary
This is a 12-week randomized, controlled trial that seeks to examine the effect of Vivo on 1) change in lower extremity strength defined as number of chair stands done in 30 seconds and 2) change in average glycemic level (HbA1c) compared to a wait list control.
Who can participate
Age range60 Years
SexALL
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Inclusion Criteria:
* Age ≥ 60 years
* Ambulatory and community-dwelling
* Diagnosis of Pre-diabetes within prior 12 months: fasting glucose between 100 to 126 OR HbA1c between 5.7 and 6.4%
* Low functioning: 1) able to do at least 1 chair stand and 2) number of chair stands done in 30 seconds is below criterion-referenced fitness standards for maintaining physical independence for age and gender
* Sedentary: less than 150 minutes of moderate physical activity OR less than 60 minutes of vigorous physical activity per week
* Have not engaged in resistance training for at least 6 months prior to enrollment
* Access to WiFi in defined exercise space
Exclusion Criteria:
* Inability to complete physical function assessment
* Use of antidiabetic medications
* Use of testosterone supplement or replacement
* Clinical disorder precluding/interfering with participation of assessments
* Unstable angina, arrhythmia, uncontrolled hypertension
* End Stage Renal Disease on Hemodialysis
* Lower extremity amputation or paralysis
* Neurological condition causing functional or pronounced cognitive impairments
* Active malignancy except for non-melanomatous skin cancers
* Weight instability (defined as gain or loss of ≥10% over the last 6 months)
* Unable to provide consent