CompletedNot Applicable

CAD-CAM or Adhesive Approaches for MIH Treatment

Turkey (Türkiye)22 participantsStarted 2020-01-15

Plain-language summary

Aim: This randomized controlled clinical study aimed to compare direct composite resin restorations and Computer Aided Design-Computer Aided Manufacturing (CAD-CAM) supported inlay or onlay restorations in young permanent molar teeth with hypomineralization. The main questions aim to answer are: * The clinical success rate of CAD-CAM supported restorations * The highest clinical success rate for restoring hypomineralized teeth. Materials and method: Children aged 6-14 years old without any systemic conditions with 32 first and second hypomineralized permanent molar teeth were included in the study. Patients were randomly distributed into 2 groups as direct composite resin restorations and CAD-CAM supported inlay or onlay restorations. All restored teeth were evaluated clinically and radiographically for 24-months. Statistical significance was accepted as p\<0.05.

Who can participate

Age range

6 Years – 14 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with first and second permanent molar teeth that have loss of more than one surface due to hypomineralization and seen with white, brown, or yellow opacities on anterior permanent teeth * Patients without any systemic, physical, physiological, or allergic conditions Exclusion Criteria: * Patients who had symptoms during the follow-up periods * Patients who did not attend follow-up appointments

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Clinical evaluation (Modified USPHS criteria- Anatomic form)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Surface roughness)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Marginal adaptation)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Marginal discoloration)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Retention)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Color stability)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Secondary caries)

Timeframe: 24 months

Trial details

NCT IDNCT06456619

SponsorBaskent University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-15

View on ClinicalTrials.gov More Molar Hypomineralization trials

Plain-language summary

Who can participate

Age range

6 Years – 14 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Clinical evaluation (Modified USPHS criteria- Anatomic form)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Surface roughness)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Marginal adaptation)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Marginal discoloration)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Retention)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Color stability)

Timeframe: 24 months

Clinical evaluation (Modified USPHS criteria-Secondary caries)

Timeframe: 24 months