CompletedNot Applicable

Post-stroke Pain taVNS

United States15 participantsStarted 2024-06-04

Plain-language summary

The purpose of this study is to explore whether a non-invasive form of ear stimulation called transcutaneous auricular vagus nerve stimulation (taVNS) can change the way participants perceive pain. Investigators will recruit up to 20 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18-80 * Have the capacity and ability to provide one's own consent in English and sign the informed consent document. * Ischemic or hemorrhagic stroke that occurred at least 6 months prior * Unilateral stroke lesions in the left hemisphere * Right upper extremity pain Exclusion Criteria: * Primary intracerebral hematoma or subarachnoid hemorrhage * Documented history of dementia * Documented history of uncontrolled depression or psychiatric disorder * Uncontrolled hypertension despite treatment, specifically SBP (Systolic Blood Pressure) / DBP (Diastolic Blood Pressure) \>=180/100mmHg * Pregnancy

What they're measuring

Thermal Pain Threshold

Timeframe: assessed during and immediately after the single 30-minute taVNS session, Post 30-minute taVNS reported

Trial details

NCT IDNCT06456385

SponsorMedical University of South Carolina

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-26

Results submitted2025-06-27

View on ClinicalTrials.gov More Stroke trials