RecruitingNot Applicable

Impact of Regular Consumption of Eggs and Nutrients Fortified Eggs on Eczema Condition in Singapore Individuals

Singapore44 participantsStarted 2024-07-17

Plain-language summary

The study aims to assess the effects of daily consumption of nutrients-fortified eggs on eczema condition in Singapore individuals with eczema. The investigators hypothesize that egg consumption will improve eczema condition and nutrients fortified egg consumption will improve further improvements when compared to standard egg consumption in individuals with eczema

Who can participate

Age range21 Years – 59 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. English-literate and able to give informed consent in English
✓. Male and female participants, aged between 21 and 59 inclusive
✓. Healthy individuals with no underlying condition or on regular medication
✓. BMI between 18.5-25 kg/m2
✓. Mild to moderate severity of eczema, which will also be determined using our questionnaires during the screening visit

Exclusion criteria

✕. Significant change in body weight (3 kg or more) in the past 3 months
✕. Significant exercise pattern over the past 3 months defined as high-intensity exercise of more than 3 hours per week
✕. Known food allergy to eggs
✕. Taking dietary supplements which may impact the study results
✕. Having gastrointestinal disorders not suitable for the study
✕. Current smokers
✕. Consumes more than 2 alcoholic drinks per day i.e. one drink is defined as either 150ml of wine, 340ml of beer/cider, or 45ml of distilled spirit
✕. Taking lipid-lowering and blood pressure-controlling medications for less than 3 years

What they're measuring

Skin questionnaires - SCORing Atopic Dermatitis (SCORAD) Index

Timeframe: Week 0, week 3, week 6, week 9, week 12

Skin questionnaires - Eczema Area and Severity Index (EASI) scoring system

Timeframe: Week 0, week 3, week 6, week 9, week 12

Skin questionnaires - Dermatology life quality index (DLQI)

Timeframe: Week 0, week 3, week 6, week 9, week 12

Skin measurement - eczema related

Timeframe: Week 0, week 3, week 6, week 9, week 12

Skin carotenoids status

Timeframe: Week 0, week 3, week 6, week 9, week 12

Blood carotenoids levels

Timeframe: Week 0, week 6, week 12

Trial details

NCT IDNCT06454942

SponsorNational University of Singapore

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11

Contact for this trial

Yuxin LIANG

6580672043 yuxinliang@u.nus.edu

View on ClinicalTrials.gov More Atopic Dermatitis Eczema trials

Plain-language summary

Who can participate

Age range21 Years – 59 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. English-literate and able to give informed consent in English
✓. Male and female participants, aged between 21 and 59 inclusive
✓. Healthy individuals with no underlying condition or on regular medication
✓. BMI between 18.5-25 kg/m2
✓. Mild to moderate severity of eczema, which will also be determined using our questionnaires during the screening visit

Exclusion criteria

✕. Significant change in body weight (3 kg or more) in the past 3 months
✕. Significant exercise pattern over the past 3 months defined as high-intensity exercise of more than 3 hours per week
✕. Known food allergy to eggs
✕. Taking dietary supplements which may impact the study results
✕. Having gastrointestinal disorders not suitable for the study
✕. Current smokers
✕. Consumes more than 2 alcoholic drinks per day i.e. one drink is defined as either 150ml of wine, 340ml of beer/cider, or 45ml of distilled spirit
✕. Taking lipid-lowering and blood pressure-controlling medications for less than 3 years

What they're measuring

Skin questionnaires - SCORing Atopic Dermatitis (SCORAD) Index

Timeframe: Week 0, week 3, week 6, week 9, week 12

Skin questionnaires - Eczema Area and Severity Index (EASI) scoring system

Timeframe: Week 0, week 3, week 6, week 9, week 12

Skin questionnaires - Dermatology life quality index (DLQI)

Timeframe: Week 0, week 3, week 6, week 9, week 12

Skin measurement - eczema related

Timeframe: Week 0, week 3, week 6, week 9, week 12

Skin carotenoids status

Timeframe: Week 0, week 3, week 6, week 9, week 12

Blood carotenoids levels

Timeframe: Week 0, week 6, week 12