Persistent pleural effusion is a life-threatening complication after cardiac surgery. The traditional treatment is chest tube drainage, which may not respond to treatment. This study introduces a new noninvasive approach for treating persistent pleural effusion using platelet-rich plasma fibrin glue (PRP-FG). This method has been successfully applied for the treatment of postoperative persistent chylothorax and pneumothorax in previous studies, which significantly decreased morbidity, mortality, and hospital stay.
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The rate of air leak that is assessed by Cerfolio classification of the air leak by a single observer
Timeframe: within 48 hours after application of platelet-rich plasma
Rate of radiolucency
Timeframe: within 48 hours after application of platelet-rich plasma
Patient hospitalization time
Timeframe: From the time the patient is admitted to the hospital to the time of discharge
Percentage of patients completely recovered
Timeframe: Through study completion, an average of 40 weeks
Percentage of untreated patients who died
Timeframe: Through study completion, an average of 40 weeks
The number of injections until the bubble stops
Timeframe: Through study completion, an average of 40 weeks