The purpose of the current investigation is to demonstrate the efficacy of high-dose furosemide plus small-volume hypertonic saline solution and a Sodium-Glucose cotransporter-2 (SGLT-2) inhibitor among patients admitted for acute exacerbation of heart failure, in determining a significant increase in diuresis and natriuresis. It is also accompanied by a rapid reduction in body weight and a substantial decrease in hospitalization length without compromising renal function.
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Diuresis from the baseline and up to 1 week
Timeframe: an average of 1 week
Natriuresis from the baseline and up to 1 week
Timeframe: an average of 1 week
Length of hospital stay
Timeframe: immediately after the intervention