Trial of JYB1904 in Patients With Allergic Asthma (NCT06438757) | Clinical Trial Compass
CompletedPhase 2
Trial of JYB1904 in Patients With Allergic Asthma
China69 participantsStarted 2024-06-19
Plain-language summary
This phase IIa trial is meant to evaluate the pharmacokinetics, pharmacodynamics and safety of JYB1904 in patients with allergic asthma.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Able to provide written informed consent voluntarily;
* Aged 18-75 years, weight ≥ 40 kg, male or female;
* Diagnosed Allergic asthma.
Exclusion Criteria:
* Prior exposure to anti-IgE therapy within 1 year;
* Allergic to anti-IgE biologics;
* Current smokers, or quit smoking within 1 year;
* Combined with other non-allergic diseases that cause IgE elevation；
* History of malignancy, autoimmune diseases, Immune complex mediated diseases, Hypereosinophilic syndrome;
* Other conditions unsuitable for the trial judged by the investigator.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this is a Phase 2 trial of JYB1904 that has already completed, what has my doctor heard about the safety results, and would any reported adverse events be a concern given my specific health history?
2This trial was measuring blood levels of IgE, which is closely tied to allergic asthma — can my doctor explain whether my own IgE levels would make me a good or poor candidate for a treatment that works this way?
3Because the trial is completed but results may not yet be published, how does my doctor suggest I weigh waiting for more data on JYB1904 against starting a standard-of-care treatment for my allergic asthma now?
4JYB1904 appears to be a new investigational drug, so can my doctor walk me through how its safety and effectiveness profile compares at this stage to existing approved biologics for allergic asthma, like anti-IgE or anti-IL-5 therapies?
5Since this trial has finished enrolling, are there any follow-on studies or expanded access options for JYB1904 that my doctor thinks would be worth exploring if this approach seems right for me?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.