Not Yet RecruitingNot Applicable

Nutritional Intervention for Sustaining Health (NURISH) Trial

72 participantsStarted 2024-06-03

Plain-language summary

The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in middle-aged adults.The main questions it aims to answer are: Does the MIND diet improve cognitive performance and heart health relative to a control diet? Researchers will compare the MIND diet group to a control (a healthy diet that does not match the MIND diet) to see if the MIND provides more benefit to health. Participants will: Consume one meal that follows the MIND diet or a control meal every day for 3 months Visit the lab before and after the 3 months of meals for tests. Keep a record of the food they eat during the study.

Who can participate

Age range45 Years – 64 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 45-64 years of age * 20/20 or corrected vision * No food allergies or intolerances * Not pregnant, lactating, or have given birth in the past 12 months * Do not smoke, use tobacco, or abuse drugs * Absence of liver or gastrointestinal diseases (i.e., primary biliary cirrhosis or gallbladder disease, chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers), hepatitis, HIV, and cancer * Not currently taking oral hypoglycemic agents, or insulin * No history of malabsorptive or bariatric surgery * Cognitively intact with no prior diagnosis of neurological disease (i.e., mild cognitive impairment, Alzheimer's disease, vascular dementia, and/or Asperger's syndrome) * Able to consume the study meals * Not enrolled in another dietary, exercise, or medication study during the study Exclusion Criteria: * Non-consent of participant * Above 64 or below 45 years of age * Vision not 20/20 or corrected * Food allergies or intolerances * Pregnant, lactating, or have given birth in the past 12 months * Smoke, use tobacco, or abuse drugs * Prior diagnosis of liver or gastrointestinal disease (i.e., primary biliary cirrhosis or gallbladder disease, chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers), hepatitis, HIV, or cancer * Currently taking oral hypoglycemic agents or …