Not Yet RecruitingEarly Phase 1

Effect of Oxycodone on Anxiety State in Painless Abortion

300 participantsStarted 2024-07-01

Plain-language summary

In this study, 300 patients who underwent painless abortion in Ruijin Hospital and sub-central hospitals were selected through a multi-center randomized controlled study, and 300 patients who underwent painless abortion in Ruijin Hospital and each sub-center hospital were divided into intravenous anesthesia with propofol with fentanyl (group F) and propofol with oxycodone (group O) by stratified group randomization method 1:1. The difference between the postoperative anxiety scores and depression scores of the two groups was observed, and the postoperative anxiety, depression and numerical pain scores were recorded. Finally, the relevant data were statistically analyzed and conclusions were drawn.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion Criteria: * Age 18-45 years old * Gestational age 6-12 weeks * American Society of Anesthesiologists （ASA） Grading I-II * Fluent communicator and able to complete self-rating scales on her own * Voluntarily participate and sign the informed consent form Exclusion Criteria: * Patients who are allergic to anesthetic drugs such as propofol, oxycodone, fentanyl, etc., or who have had other anesthetic adverse events * Patients with anxiety or depression * Presence of organic mental disorders, mental retardation * Severe acute and chronic infection, severe heart, liver and kidney insufficiency * Patients with complications or bleeding \> 50ml during surgery

What they're measuring

anxiety scores

Timeframe: 20-30 minutes postoperative

Trial details

NCT IDNCT06435949

SponsorRuijin Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-30

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