Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affecte… (NCT06430268) | Clinical Trial Compass
By InvitationNot Applicable
Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants
United States90 participantsStarted 2024-05-21
Plain-language summary
This study will compare 2 methods to clean contaminated implant surfaces: air-polishing device versus titanium curette. Both of these methods will be used in the non-surgical and surgical setting, followed by implant removal. Then, in-vitro analysis to assess the efficacy of surface decontamination will be performed.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* Adult individuals between 18 and 80 years of age who require the explantation of at least one titanium or titanium alloy implant due to severe peri-implantitis (\> 50% bone loss and signs of inflammation);
* Individuals who did not undergo surgical or non-surgical peri-implant therapy in the previous 6 months.
Exclusion criteria:
* Acute infection associated with adjacent teeth;
* Any technical complication that does not allow implant removal using a reverse torque device;
* Active infectious diseases of any kind;
* Medical conditions which requires premedication prior to dental treatments/visits;
* Pregnant women or planning to become pregnant (self-reported);
* History of radiotherapy in the head and neck or chemotherapy in the last 3 years;
* Any other diseases or medications that may contraindicate the surgical procedure or compromise wound healing.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Percentage of clean implant surface area following implant decontamination approaches
Timeframe: Right after decontamination and implant removal (T0)