CompletedNot Applicable

The Role of GIP in Postprandial Splanchnic Blood Flow Distribution and Metabolism in Patients With Type 2 Diabetes

Denmark10 participantsStarted 2023-11-01

Plain-language summary

This project will describe the mechanisms of action and the relative contributions of GIP to changes in gastrointestinal blood flow induced by oral glucose and endogenous GIP with the use of a receptor antagonists GIP(3-30)NH2 in patients with type 2 diabetes.

Who can participate

Age range20 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Type 2 diabetes * BMI 20-35 kg/m\^2 * Age 20-80 Exclusion Criteria: * Not MRI-compatible implants * Claustrophobia * Abnormal kidney or liver function * Anemia * Planned weight loss or change in diet * Hypertension * Other conditions that could be expected to affect the primary or secondary outcomes

What they're measuring

Redistribution of splanchnic blood flow in the vessel mesenteric superior artery (functional MRI)

Timeframe: 80 minutes

Trial details

NCT IDNCT06426823

SponsorUniversity of Copenhagen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-16

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