The present longitudinal, randomized, and blinded clinical trial aims to: * Evaluate the effects of resistance training on the functional capacity, quality of life, and cardiac biomarkers of hospitalized patients with heart failure (HF) on the waiting list for heart transplantation (HTx). * Evaluate the associations between Fried's frailty classification and functional capacity responses to resistance training. The protocol will have a total duration of 12 weeks.
Age range
18 Years – 70 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
To investigate changes in physical performance measured by Six-Minute Walk Test.
Timeframe: The data will be collected on the baseline (T0), at 6 weeks (T1), and at 12 weeks (T2).
To investigate changes in physical performance measured by Short Physical Performance Battery (SPPB).
Timeframe: The data will be collected on the baseline (T0), at 6 weeks (T1), and at 12 weeks (T2).
To investigate changes in respiratory muscle strength:
Timeframe: The data will be collected on the baseline (T0), at 6 weeks (T1), and at 12 weeks (T2).
To investigate changes in peripheral muscle strength.
Timeframe: The data will be collected on the baseline (T0), at 6 weeks (T1), and at 12 weeks (T2).
To investigate changes in quality of life:
Timeframe: The data will be collected on the baseline (T0), at 6 weeks (T1), and at 12 weeks (T2).
Enhancing the investigation of changes in cardiac biomarker ketones
Timeframe: The data will be collected on the baseline (T0), at 6 weeks (T1), and at 12 weeks (T2).
Enhancing the investigation of changes in cardiac biomarker brain natriuretic peptide
Timeframe: The data will be collected on the baseline (T0), at 6 weeks (T1), and at 12 weeks (T2).