Not Yet RecruitingNot Applicable

Microfragmented Adipose Tissue Injection Compared to Hyaluronic Acid for Treatment of Temporomandibular Joint Osteoarthritis

28 participantsStarted 2024-06-01

Plain-language summary

Internal derangement and osteoarthritis are the most common degenerative temporomandibular joint diseases and initial treatment for such conditions relies on arthrocentesis. Micro fragmentation of adipose tissue has been proven in orthopedic literature to represent a more effective method to preserve stem cells, but no application has ever been reported in the temporomandibular joint.

Who can participate

Age range14 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * \* TMJ osteoarthritis assessed by clinical examination and MRI imaging * Presence of TMJ-related symptoms including at least limited mouth opening and joint pain * Previously failed conservative treatment * Age superior to 14 years * No previous TMJ surgical procedures * Acquisition of informed consent; * Complete availability of the data acquired preoperatively and during each follow-up * Patients free from any systemic disease that may affect the procedure. Exclusion Criteria: * \* Previously diagnosed hematological and neurological conditions; * Previous malignant head and neck neoplasms; * Contraindication to fat harvesting. * Uncooperative patients.

What they're measuring

VAS

Timeframe: 3 months

Trial details

NCT IDNCT06425263

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-01

View on ClinicalTrials.gov More Temporomandibular Joint Osteoarthritis trials