CompletedPhase 2

Effect of Nicorandil in Type 2 Diabetic Obese Patients

Egypt46 participantsStarted 2023-11-01

Plain-language summary

1. Evaluating the effect of nicorandil on glycemic control of diabetic obese patients treated with sulfonylureas. 2. Investigating the effect of nicorandil on body weight of diabetic obese patients treated with sulfonylureas.

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients newly diagnosed with diabetes . * Body mass index (BMI) \>30 Kg/m2. * The selected patients are treated with sulfonylureas alone. * The age of selected patient ranged from 18 and 60 years. Exclusion Criteria: * Pregnant and lactating females. * Patients with hypersensitivity to nicorandil. * Uncontrolled hypertension and its antihypertensive medications * Severe renal or hepatic disease.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in HbA1c level

Timeframe: The participants will be assessed before initiation of the study (baseline), and at the end of the study after 3 months.

Change in body weight.

Timeframe: The participants will be assessed before initiation of the study (baseline), and at the end of the study after 3 months.

Change in Body mass index (BMI)

Timeframe: The participants will be assessed before initiation of the study (baseline), and at the end of the study after 3 months.

Change in Visceral adiposity index (VAI).

Timeframe: The participants will be assessed before initiation of the study (baseline), and at the end of the study after 3 months.

Trial details

NCT IDNCT06423729

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07-30

View on ClinicalTrials.gov More Diabetes Mellitus, Type 2 trials

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in HbA1c level

Timeframe: The participants will be assessed before initiation of the study (baseline), and at the end of the study after 3 months.

Change in body weight.

Timeframe: The participants will be assessed before initiation of the study (baseline), and at the end of the study after 3 months.

Change in Body mass index (BMI)

Timeframe: The participants will be assessed before initiation of the study (baseline), and at the end of the study after 3 months.

Change in Visceral adiposity index (VAI).

Timeframe: The participants will be assessed before initiation of the study (baseline), and at the end of the study after 3 months.