Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder

Inclusion Criteria: * Between age 25 and 75. * Current DSM-5 diagnosis of moderate to severe AUD (≥4 diagnostic symptoms). * Able to attend scheduled clinic visits * Able to read, understand and voluntarily sign Informed Consent prior to participating in any study-specific procedures or assessments. * If on a medication regimen, that regimen will be stable for the duration of the study; * Fluency in English. Exclusion Criteria: * Transcranial magnetic stimulation (TMS) and magnetic resonance imaging (MRI) contraindications: such as a cardiac pacemaker, cochlear implant, or an implanted device (deep brain stimulation, metal in the head, metal in the body, claustrophobia, pregnant or breastfeeding or other ferromagnetic device/objected in the head and body within 30 cm of the treatment coil. * General medical condition, disease or neurological disorder that interferes with the assessments or participation. * Unable to safely withdraw, at least two weeks prior to treatment, from medications that increase seizure risk. * Current substance abuse (except caffeine or nicotine) as determined by positive toxicology screen. * Have a mass lesion, cerebral infarct, or other active CNS disease, including an alcohol-related seizure or a seizure disorder. • A recent suicide attempt (defined as within the last 30 days) or presence of current suicidal plan or intent. Patients at risk for suicide will be required to establish a written safety plan involving their primary therapist before en…