RecruitingNot Applicable

Remote Delivery of a Mindfulness-based Intervention for Tics

United States150 participantsStarted 2024-05-23

Plain-language summary

This research study is being done to compare a mindfulness-based intervention for tics (MBIT) to psychoeducation with relaxation and supportive therapy (PRST) for individuals with Tourette's syndrome or Persistent Tic Disorders (collectively TS). It is the investigator's hope that this information cam be used to improve current treatments for individuals with TS.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. be ≥18 years of age;
✓. meet diagnostic criteria for a primary or co-primary diagnosis of Tourette Syndrome or a Persistent Motor or Vocal Tic Disorder on a structured clinical interview;
✓. have moderate or greater tic severity as evidenced by a YGTSS Total Tic Score of \>14 (when motor and vocal tics are present) or \>10 (when only motor or vocal tics are present);
✓. be medication free and/or on a stable dose of psychiatric medication 8 weeks prior to study participation;
✓. be not engaged in psychotherapy for non-TS conditions and/or be on a stable course of therapy for 6 months prior to study participation
✓. be fluent in English;
✓. have access to a smart phone and/or tablet.

Exclusion criteria

✕. a current diagnosis of substance use disorder, psychosis, mania or another condition that requires another form of care;
✕. severe current suicidal/homicidal ideation and/or self-injury requiring medical intervention;
✕. concurrent psychotherapy for TS;
✕. prior extensive experience with mindfulness and/or meditation.

What they're measuring

Yale Global Tic Severity Scale (YGTSS) Total Tic Severity Score

Timeframe: Screen, Baseline (Week 0), Mid-treatment (Week 5), Post-treatment (Week 9), 1-month follow-up (Week 13), 3-month follow-up (Week 22), and 6-month follow-up (Week 35)

Trial details

NCT IDNCT06408662

SponsorJohns Hopkins University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-06

Contact for this trial

Lauren Browning

443-300-8836 mbit@jh.edu

View on ClinicalTrials.gov More Tourette Syndrome trials