CompletedNot Applicable

Gastric Emptying After Sleeve Gastrectomy

Netherlands18 participantsStarted 2022-05-10

Plain-language summary

Sleeve gastrectomy (SG) increases gastrointestinal motility, which influences feelings of fullness and satiety. By understanding the differences in gastric emptying (GE) between patients with sufficient weight loss (Total weight loss \[TWL\] \> 35%) and insufficient weight loss (TWL \< 25%), better insight in the aetiology of weight loss after sleeve gastrectomy may be obtained. GE will be measured with scintigraphy and MRI.

Who can participate

Age range18 Years – 55 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women aged between 20 and 55 years who underwent sleeve gastrectomy as primary procedure with either TWL \< 25% or TWL \> 35%. * Patients who had a follow-up period of 2-3 years after sleeve gastrectomy Exclusion Criteria: * Maximum BMI \>50 kg/m2 * Patients with a disease known to affect appetite, gastric emptying or gastrointestinal motility * Patients who are unable to stop medications that affect gastric emptying and/or motility prior to measurements. It is depending on t1/2 for how long they need to stop medication * Patients who started menopause * Patients with gastrointestinal problems or, gastric or intestinal diseases * Patients with a drug or alcohol addiction * Patients who are unable to stop smoking for 24h * Patients who are pregnant or lactating * Patients who have an intolerance or allergy for one of the components of the test product * Patients who have a contra-indication to MRI scanning

What they're measuring

Gastric emptying compared between patients with poor and successful weight loss

Timeframe: 2-3 years

Gastric emptying compared between measured with MRI and scintigraphy

Timeframe: 2-3 years

Trial details

NCT IDNCT06407193

SponsorRijnstate Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-03-30