CompletedNot Applicable

Gastric Emptying After Sleeve Gastrectomy

Netherlands18 participantsStarted 2022-05-10

Plain-language summary

Sleeve gastrectomy (SG) increases gastrointestinal motility, which influences feelings of fullness and satiety. By understanding the differences in gastric emptying (GE) between patients with sufficient weight loss (Total weight loss \[TWL\] \> 35%) and insufficient weight loss (TWL \< 25%), better insight in the aetiology of weight loss after sleeve gastrectomy may be obtained. GE will be measured with scintigraphy and MRI.

Who can participate

Age range

18 Years – 55 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women aged between 20 and 55 years who underwent sleeve gastrectomy as primary procedure with either TWL \< 25% or TWL \> 35%. * Patients who had a follow-up period of 2-3 years after sleeve gastrectomy Exclusion Criteria: * Maximum BMI \>50 kg/m2 * Patients with a disease known to affect appetite, gastric emptying or gastrointestinal motility * Patients who are unable to stop medications that affect gastric emptying and/or motility prior to measurements. It is depending on t1/2 for how long they need to stop medication * Patients who started menopause * Patients with gastrointestinal problems or, gastric or intestinal diseases * Patients with a drug or alcohol addiction * Patients who are unable to stop smoking for 24h * Patients who are pregnant or lactating * Patients who have an intolerance or allergy for one of the components of the test product * Patients who have a contra-indication to MRI scanning

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Gastric emptying compared between patients with poor and successful weight loss

Timeframe: 2-3 years

Gastric emptying compared between measured with MRI and scintigraphy

Timeframe: 2-3 years

Trial details

NCT IDNCT06407193

SponsorRijnstate Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-03-30

View on ClinicalTrials.gov More Gastric Emptying trials