CompletedPhase 1/2

Does Successive Intra-articular Injections of Tenoxicam or Meloxicam Affect Treatment of TMJ Displacement

Egypt30 participantsStarted 2024-06-01

Plain-language summary

The temporomandibular joint's (TMJ) articular disc, situated between the mandibular condyle's convexity and the articular tubercle's slope, is the most intricate synovial articulation in the human body. While the usual discal position as defined by magnetic resonance imaging (MRI) places the posterior discal band at the 12 o'clock position atop the mandibular condyle's maximum convexity, this discal disposition is altered in over 30% of the population without any accompanying physical symptoms. This denotes that rather than correcting the anatomical disc position, the treatment for discal displacement would primarily focus on symptom relief.

Who can participate

Age range18 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients of both sexes with an age range of 18-45 years.
✓. Those patients with the radiographic interpretation of unilateral or bilateral (TMJ) anterior disc displacement with reduction with the clinical signs of pain, limitation of mouth opening, and TMJ clicking; Wilkes classification type II.

Exclusion criteria

✕. Clinical or radiographic signs of disc displacement without reduction, osteoarthritis, or articular bony changes.
✕. Previous (TMJ) surgery, arthrocentesis, or occlusal splints.
✕. Any systemic disease affecting the temporomandibular joint's anatomy, mechanical function, or outcome of the proposed treatment.
✕. Those Patients with a history of allergic reactions to any components of the injectable solutions.

What they're measuring

Clicking

Timeframe: 9 months

Visual analogue scale

Timeframe: 9 months

Maximal interincisal opening

Timeframe: 9 months

Trial details

NCT IDNCT06403046

SponsorBeni-Suef University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-07

View on ClinicalTrials.gov More Temporomandibular Joint Disc Displacement, With Reduction trials

Plain-language summary

Who can participate

Age range18 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients of both sexes with an age range of 18-45 years.
✓. Those patients with the radiographic interpretation of unilateral or bilateral (TMJ) anterior disc displacement with reduction with the clinical signs of pain, limitation of mouth opening, and TMJ clicking; Wilkes classification type II.

Exclusion criteria

✕. Clinical or radiographic signs of disc displacement without reduction, osteoarthritis, or articular bony changes.
✕. Previous (TMJ) surgery, arthrocentesis, or occlusal splints.
✕. Any systemic disease affecting the temporomandibular joint's anatomy, mechanical function, or outcome of the proposed treatment.
✕. Those Patients with a history of allergic reactions to any components of the injectable solutions.