RecruitingNot Applicable

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

United States2,600 participantsStarted 2024-09-03

Plain-language summary

This project aims to collect detailed clinical data, blood samples, and patient-reported outcomes from 2,600 lung transplant candidates, donors, and recipients at Lung Transplant Centers. The goal is to create a robust resource for various research objectives, including studying the impact of variations in donor and medical practices on clinical outcomes. The project also seeks to identify serum biomarkers associated with or predictive of specific post-transplant complications and conditions.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Able to understand and provide informed consent
✓. ≥ 18 years of age at the time of written informed consent
✓. Anticipated listing or listed for a single or bilateral cadaveric donor lung transplant or having received a lung transplant within 30 days

Exclusion criteria

✕. Unwillingness of a participant or legally authorized representative (LAR) to give written informed consent or comply with study protocol
✕. Pregnancy or plans to become pregnant
✕. Past or current medical problems or findings from physical examination or laboratory testing, which, in the opinion of the investigator, may pose additional risks from participation in the study, may interfere with the participant's ability to comply with study requirements or that may impact the quality or interpretation of the data obtained from the study.

What they're measuring

Number of participants enrolled and critical variable completeness

Timeframe: 3 years

Number of PROs collected per patient

Timeframe: 3 years

Number of specimens per participant collected

Timeframe: 3 years

Trial details

NCT IDNCT06399302

SponsorDuke University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-06-30

Contact for this trial

Allyn Damman

919-259-4414 allyn.damman@duke.edu

View on ClinicalTrials.gov More Lung Transplant; Complications trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Able to understand and provide informed consent
✓. ≥ 18 years of age at the time of written informed consent
✓. Anticipated listing or listed for a single or bilateral cadaveric donor lung transplant or having received a lung transplant within 30 days

Exclusion criteria

✕. Unwillingness of a participant or legally authorized representative (LAR) to give written informed consent or comply with study protocol
✕. Pregnancy or plans to become pregnant
✕. Past or current medical problems or findings from physical examination or laboratory testing, which, in the opinion of the investigator, may pose additional risks from participation in the study, may interfere with the participant's ability to comply with study requirements or that may impact the quality or interpretation of the data obtained from the study.