CompletedPhase 4

Esketamine and Butorphanol for Post-Lobectomy Pain

China223 participantsStarted 2022-03-01

Plain-language summary

Post-thoracotomy pain syndrome (PTPS) affects respiratory function, hindering sputum clearance and ventilation, and represents a significant complication of thoracic surgery. The analgesic effect of esketamine combined with butorphanol in PTPS is still unclear, so this study focused on this aspect.

Who can participate

Age range20 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 20-70 years * Classified as American Society of Anesthesiologists I-III * Undergoing video-assisted lobectomy Exclusion Criteria: * Operative duration \< 1 hour * Significant comorbidities affecting vital organs such as liver, kidney, and heart * Severe infections * Immunodeficiency * Coagulation disorders * History of analgesic drug abuse * Severe dementia or communication barriers * Mental illnesses.

What they're measuring

Incidence of chronic pain

Timeframe: 3 months post-surgery

Trial details

NCT IDNCT06398834

SponsorSecond People's Hospital of Hefei City

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-10-01

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