RecruitingPhase 4

Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2

Canada60 participantsStarted 2024-09-26

Plain-language summary

OK-TRANSPLANT 2 is a vanguard study for a large randomized, pragmatic, open-label trial. We will randomize participants with obesity, high-risk CKD/dialysis who are hoping for lose weight for the purpose of kidney transplant. Subjects will either be enrolled on a virtual weight management program or continue their usual care.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults aged 18 years or older * BMI \> 35 kg/m\^2 * \>10% risk of ESKD requiring renal replacement therapy over 2 years or receiving dialysis Exclusion Criteria: * Known contraindication to a GLP-1RA * Type 1 diabetes * No access to semaglutide via drug coverage * Absolute contraindication to kidney transplant * Pregnant, breastfeeding or planning to become pregnant * Currently in a GLP-1RA or GLP-1RA/GIP study or planning to be in one

What they're measuring

Feasibility of Recruitment

Timeframe: 12 months

Trial details

NCT IDNCT06396416

SponsorWestern University, Canada

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02

Contact for this trial

Heather LaPier, BSc

519-646-6100 heather.lapier@sjhc.london.on.ca

View on ClinicalTrials.gov More Obesity trials