CompletedEarly Phase 1

Comparing Direct and Indirect Detection Methods of Multiple Routes of Testosterone Administration

United States14 participantsStarted 2024-11-27

Plain-language summary

Testosterone abuse is extremely prevalent in athletes globally and especially in the United States professional sporting leagues

Who can participate

Age range18 Years – 60 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * HEALTHY MALE ADULTS, AGED 18-60 YEARS Exclusion Criteria: * Individuals currently enrolled in a registered testing pool for anti-doping purposes * Unwilling to provide urine or blood samples * Individuals who are not actively exercising * Individuals who show a high risk of heart attack or cardiovascular disease as defined by a physician * Individuals that have an elevated baseline hematocrit as determined by the PI * Individuals who are diabetic or are currently taking diabetic medications. * Individuals that have donated blood (approximately 500 mL) in the past 8 weeks * Individuals with severe acne * Individuals with a history of cancer, cardiac, renal or hepatic disease

What they're measuring

Detection windows of testosterone administered via injection, oral and skin cream.

Timeframe: 12 weeks

Changes in serum concentration of testosterone

Timeframe: 12 weeks

Changes in serum concentration of androstenedione

Timeframe: 12 weeks

Changes in serum concentration of luteinizing hormone

Timeframe: 12 weeks

Trial details

NCT IDNCT06393634

SponsorSports Medicine Research and Testing Laboratory

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2024-11-27

View on ClinicalTrials.gov More Healthy trials