CompletedEarly Phase 1

Comparing Direct and Indirect Detection Methods of Multiple Routes of Testosterone Administration

United States14 participantsStarted 2024-11-27

Plain-language summary

Testosterone abuse is extremely prevalent in athletes globally and especially in the United States professional sporting leagues

Who can participate

Age range

18 Years – 60 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * HEALTHY MALE ADULTS, AGED 18-60 YEARS Exclusion Criteria: * Individuals currently enrolled in a registered testing pool for anti-doping purposes * Unwilling to provide urine or blood samples * Individuals who are not actively exercising * Individuals who show a high risk of heart attack or cardiovascular disease as defined by a physician * Individuals that have an elevated baseline hematocrit as determined by the PI * Individuals who are diabetic or are currently taking diabetic medications. * Individuals that have donated blood (approximately 500 mL) in the past 8 weeks * Individuals with severe acne * Individuals with a history of cancer, cardiac, renal or hepatic disease

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Detection windows of testosterone administered via injection, oral and skin cream.

Timeframe: 12 weeks

Changes in serum concentration of testosterone

Timeframe: 12 weeks

Changes in serum concentration of androstenedione

Timeframe: 12 weeks

Changes in serum concentration of luteinizing hormone

Timeframe: 12 weeks

Trial details

NCT IDNCT06393634

SponsorSports Medicine Research and Testing Laboratory

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2024-11-27

View on ClinicalTrials.gov More Healthy trials

Who can participate

Age range

18 Years – 60 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Detection windows of testosterone administered via injection, oral and skin cream.

Timeframe: 12 weeks

Changes in serum concentration of testosterone

Timeframe: 12 weeks

Changes in serum concentration of androstenedione

Timeframe: 12 weeks

Changes in serum concentration of luteinizing hormone

Timeframe: 12 weeks