CompletedNot Applicable

Uterine Artery Diastolic Notching & Apelin-13 and 36

Turkey (Türkiye)88 participantsStarted 2023-03-01

Plain-language summary

This study was conducted to investigate the relationship between diastolic notching on uterine artery Doppler and serum apelin-13 and 36 concentrations between 11 and 14 weeks of gestation.

Who can participate

Age range

18 Years – 39 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Nonsmokers,
. Singleton pregnancies between 11 and 14 weeks of gestation
. Pregnant women who did not conceive with assisted reproductive methods

Exclusion criteria

. Smokers
. Pregnant women who conceived with assisted reproductive techniques
. Pregnant women with multiple pregnancies
. Pregnant women who started with multiples and continued with singletons
. Pregnant women with any pregestational disease, thrombophilia
. Pregnant women with any congenital uterine anomaly
. Pregnant women with a history of recurrent pregnancy loss
. Pregnant women using aspirin or heparin

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Relationship between diastolic notching on uterine artery Doppler and serum apelin-13 and apelin-36 concentrations.

Timeframe: through study completion, an average of 1 year

Relationship between high pulsatility index on uterine artery Doppler and serum apelin-13 and apelin-36 concentrations.

Timeframe: through study completion, an average of 1 year

Trial details

NCT IDNCT06390202

SponsorUmraniye Education and Research Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2023-10-30

View on ClinicalTrials.gov More Diagnosis trials

Who can participate

Age range

18 Years – 39 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Nonsmokers,
. Singleton pregnancies between 11 and 14 weeks of gestation
. Pregnant women who did not conceive with assisted reproductive methods

Exclusion criteria

. Smokers
. Pregnant women who conceived with assisted reproductive techniques
. Pregnant women with multiple pregnancies
. Pregnant women who started with multiples and continued with singletons
. Pregnant women with any pregestational disease, thrombophilia
. Pregnant women with any congenital uterine anomaly
. Pregnant women with a history of recurrent pregnancy loss
. Pregnant women using aspirin or heparin

What they're measuring

Relationship between diastolic notching on uterine artery Doppler and serum apelin-13 and apelin-36 concentrations.

Timeframe: through study completion, an average of 1 year

Relationship between high pulsatility index on uterine artery Doppler and serum apelin-13 and apelin-36 concentrations.

Timeframe: through study completion, an average of 1 year