Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury (NCT06386120) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury
80 participantsStarted 2024-05
Plain-language summary
The goal of this observational study is to learn about EIT in observing the application of lung protective ventilation strategies in patients with pulmonary contusion, particularly the impact on pulmonary ventilation blood flow ratio, oxygen, and condition. The main question it aims to answer is:
Can lung protective ventilation strategies improve respiratory function in patients with severe chest contusion? We will collect clinical data of participants who already taking lung protective ventilation strategies as part of their regular medical care.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with severe chest contusion admitted to the intensive care unit (ICU);
* Abbreviated Injury Scale (AIS) ≥ 3 and/or Blunt Pulmonary Contusion 18 score (BPC18) ≥ 3;
* Age range from 18 to 90 years old;
* Mechanical ventilation;
* Stay in the ICU for less than 12 hours.
Exclusion Criteria:
* Perinatal women;
* Expected to be mechanically ventilated for less than 48 h;
* Expected duration of stay in the ICU is less than 24 hours;
* There are contraindications for the use of EIT (pacemaker implantation, local skin wounds after chest surgery, etc.);
* Accept extracorporeal membrane oxygenator;
* Mechanical ventilation\>7 days;
* Confirmed ventilator-associated pneumonia;
* Pneumothorax without drainage or presence of subcutaneous emphysema.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
ventilation blood flow ratio
Timeframe: through study completion, an average of 1 year