At present, there are limited data on perioperative efficacy of barbiturates at home and abroad. The purpose of this clinical trial is to observe the effects of amobarbital sodium combined with low-dose propofol on hemodynamics during induction and perioperative adverse reactions in gynecological laparoscopic surgery patients, and to provide a more reasonable, safe and comfortable anesthesia program for female patients who undergoing laparoscopic surgery. The main questions it aims to answer are: * whether the combination of the two results on more stable hemodynamics during induction in gynecological laparoscopic surgery patients; * whether the incidence of perioperative oxidative stress and inflammation and postoperative nausea and vomiting（ponv） improved after the use of the two combinations of anesthesia induction. Participants will: * Induction of anesthesia with the experimental drug or placebo； * 5 ml of venous blood was retained before, after, and 1 day after surgery for follow-up determination of serum associated factor levels； * To record their vital signs at any point during the anaesthetic process; Serum serological indexes related to oxidative stress and inflammation were determined. The agitation during the recovery period was recorded. The incidence and severity of ponv were recorded at 2h, 2-6h, and 6-24h postoperatively, and the use of palonosetron was also recorded.
Age range
40 Years – 60 Years
Sex
ALL
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Mean arterial pressure (MAP) during Induction of anesthesia
Timeframe: Up to 3 hours