UnknownNot Applicable

IVF Failure and Pregnancy Loss on Couples' Psychological Stress

China150 participantsStarted 2024-05-01

Plain-language summary

The goal of this observational study is to learn about The purpose of this study was to compare the psychological differences between couples after IVF transplant failure and IVF pregnancy loss, including the differences in anxiety, depression, stress and post-traumatic stress between women and their spouses. The main question it aims to answer is: What are the psychological effects of IVF implantation failure and IVF pregnancy loss on women and the psychological differences between couples? Participants already taking IVF as part of their regular medical care will answer online survey questions about their joint pain for 1 years.

Who can participate

Age range

20 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Couples who have undergone IVF at our center and have completed at least 1 embryo transfer.
. Female age 20-45 years, male age 22-45 years.

Exclusion criteria

. Couples with contraindications to pregnancy.
. Couples who undergo donor IVF.
. Infertility women caused by organic lesions.
. Couples with previous mental disorders.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

As the number of failed IVF implants increases, does it increase the difference in anxiety and depression between couples?

Timeframe: 1 year

As the number of failed IVF implants increases, does it increase the difference in fertility stress between couples?

Timeframe: 1 year

Does pregnancy loss after IVF transplantation have a differential effect on anxiety and depression between couples?

Timeframe: 1 year

Does pregnancy loss after IVF transplantation have a differential effect on post-traumatic stress responses between couples?

Timeframe: 1 year

Trial details

NCT IDNCT06385444

SponsorThe First Hospital of Jilin University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-05-01

Contact for this trial

Qi Xi, doctorate

15804303801 xiqi@jlu.edu.cn

View on ClinicalTrials.gov More Fertilization in Vitro trials

Plain-language summary

Who can participate

Age range

20 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Couples who have undergone IVF at our center and have completed at least 1 embryo transfer.
. Female age 20-45 years, male age 22-45 years.

Exclusion criteria

. Couples with contraindications to pregnancy.
. Couples who undergo donor IVF.
. Infertility women caused by organic lesions.
. Couples with previous mental disorders.

What they're measuring

As the number of failed IVF implants increases, does it increase the difference in anxiety and depression between couples?

Timeframe: 1 year

As the number of failed IVF implants increases, does it increase the difference in fertility stress between couples?

Timeframe: 1 year

Does pregnancy loss after IVF transplantation have a differential effect on anxiety and depression between couples?

Timeframe: 1 year

Does pregnancy loss after IVF transplantation have a differential effect on post-traumatic stress responses between couples?

Timeframe: 1 year