Indoor Air Quality, Temperature and Cognitive Performance (NCT06380582) | Clinical Trial Compass
CompletedNot Applicable
Indoor Air Quality, Temperature and Cognitive Performance
Netherlands18 participantsStarted 2024-04-25
Plain-language summary
Study design: A cross-over single-blinded treatment design will be used. Participants will undergo 4 different conditions: (1) low air flow and 23°C, (2) low air flow and 35°C, (3) high air flow and 23°C, and (4) high air flow and 35°C. Participants will be blinded to the air quality level; however, it is not possible to blind them to the temperature condition, as they will be able to perceive it as different.
Study population: The population consists of healthy young and middle-aged adults of both sexes between 18 and 40 years.
Intervention (if applicable): Each participant undergoes 4 conditions in randomized order. Two conditions consist of poor air quality defined as 3,000 ppm carbon dioxide and 23°C or 35°C temperature, respectively.
Who can participate
Age range18 Years – 40 Years
SexALL
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Inclusion Criteria:
* Adults between 18 to 40 years old
* Western-European background
* Generally healthy
* No medication which may influence the outcome parameters. This will be determined on a case-by-case basis. Contraceptive uses for women are allowed and will be verified through a questionnaire.
* Non-smokers or persons who quit smoking more than five years ago
Exclusion Criteria:
Participants, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician will be informed, cannot participate in this study
* Individuals with a diagnosed physical or mental disability or attention deficit hyperactivity disorder (ADHD) or depression
* Any medication or medical condition that might interfere with the physiological outcome parameters or in some regards impair cognition
* Unstable body weight (weight gain or loss \>3kg in the past three months)
* Participation in another biomedical study within 1 month prior to screening visit
* Shift workers
* Colour blindness
* Pregnancy
* People with a low haemoglobin or haematocrit concentration
* Not having visited or resided in a warm country in the last 3 months
* Participants with asthma or restricted lung function due to allergies