Not Yet RecruitingNot Applicable

Cardiopulmonary Changes Following Spinal Cord Stimulation in Individuals With Spinal Cord Injury

Canada22 participantsStarted 2024-08-01

Plain-language summary

The aim of this study is to examine the mechanisms of transcutaneous spinal cord stimulation (tSCS) for improving cardiovascular and pulmonary function in individuals with chronic motor-complete spinal cord injury (SCI) by measuring vascular related endothelial biomarkers, plasma catecholamines, and respiratory parameters.

Who can participate

Age range19 Years – 65 Years

SexALL

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Exclusion criteria

✕. Resident of British Columbia, Canada with active provincial medical services plan
✕. Male or female, 19-65 years of age
✕. Chronic SCI at or above the T10 spinal cord segment
✕. \>1-year post injury or diagnosis, at least 6 months from any spinal surgery.
✕. American Spinal Injury Association Impairment Scale (AIS) A, B, C and D for SCI
✕. Stable management of spinal cord related clinical issues (e.g., spasticity management)
✕. Women of childbearing potential must not be intending to become pregnant, currently pregnant, or lactating. The following conditions apply:
✕.1 Women of childbearing potential must have a confirmed negative pregnancy test prior to the baseline visit.

What they're measuring

Circulating endothelial biomarkers in EMV/µL (Park et al., 2023)

Timeframe: Real-time Effect: 1 week; Long-term Effect: 8 weeks

Trial details

NCT IDNCT06379711

SponsorUniversity of British Columbia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-08-01

Contact for this trial

Andrea Maharaj, BSc

6046758856 amaharaj@icord.org

View on ClinicalTrials.gov More Spinal Cord Injuries trials