UnknownPhase 2/3

A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible Bronchoscopy

India1,050 participantsStarted 2024-04-24

Plain-language summary

No study has examined the role of inhaled glycopyrrolate on mucus secretion. We hypothesize that nebulized glycopyrrolate will improve bronchoscopy procedure by effectively suppressing airway mucus secretion, thereby decreasing cough, and thus improving patient comfort during bronchoscopy. In this study, we aim to compare the efficacy of nebulized glycopyrrolate versus nebulized ipratropium in suppression of cough during flexible bronchoscopy.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Consecutive patients with indication for flexible bronchoscopy will be enrolled in the study if they meet all the following criteria: * age ≥18 years * hemodynamically stable * willing to provide a written informed consent Exclusion Criteria: Patients with any of the following will be excluded: * intubated or tracheostomized patients * patients with airway stent in situ * patients with a history of glaucoma * baseline oxygen saturation \<90% * patients with hemodynamic instability (SBP \<90 mm Hg) * patients undergoing sedation for bronchoscopy * failure to provide informed consent

What they're measuring

Cough count

Timeframe: Intra-procedure

Trial details

NCT IDNCT06376942

SponsorPost Graduate Institute of Medical Education and Research, Chandigarh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-04-25

Contact for this trial

Ritesh Agarwal

7087007625 agarwal.ritesh@outlook.in

View on ClinicalTrials.gov More Subjects Undergoing Flexible Bronchoscopy trials