Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints

Inclusion Criteria: * Men and women age ≥ 25 years * Radiologically confirmed and symptomatic thumb basal joint osteoarthritis (OA) planned for trapeziectomy Exclusion Criteria: * Previous surgery to the affected thumb basal joint * Post-traumatic thumb basal joint OA * Rheumatoid arthritis or other chronic inflammatory arthritis, history of psoriasis affecting joints, gout or pseudogout * Ongoing infection in the hand or wrist * Inability to co-operate with the follow-up protocol or to assimilate information about the study protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction) * Systemic or intra-articular glucocorticoids or intraarticular platelet-rich plasma or hyaluronic acid injections in the affected joint within 3 months prior to enrollment