CompletedNot Applicable

Effect of Xylitol-based Chewing Gums, Sugar-free and Sugared, on Salivary Flow and pH in Young Adults

Ecuador100 participantsStarted 2023-12-12

Plain-language summary

This study was planned to evaluate the effects of xylitol-based chewing gums, sugar-free and sugared, on salivary flow and pH in young adults.

Who can participate

Age range

18 Years – 25 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants must meet at least 20 teeth. * Providing written informed consent. and being willing to comply with the study procedures. * Being willing to comply with the study procedures Exclusion Criteria: * Individuals with systemic, infectious, or inflammatory diseases * Individuals who are taking medications, antibiotics, or fluoride in the last month. * Regular consumers of products and mouthwashes containing xylitol or sorbitol. * Individuals with abnormal salivary flow (\<1 ml/min). * Pregnant women or those on contraceptive pill treatment. * Individuals with abnormal dietary habits. * Subjects with periodontal disease or presence of dental caries.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

G1: Gum of xilytol

Timeframe: The trial period for each participant is 35 minutes in total. Salivary pH at 10 minutes, salivary pH at 20 minutes, salivary pH at 30 minutes. Basal salivary volume and salivary volume at 35 minutes.

G2: Gum of sugar free

G3: Gum of sugar

G4: Parafinn wax

Trial details

NCT IDNCT06370091

SponsorUniversidad Católica de Cuenca

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-31

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