The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving pressure-guided lung protective ventilation can reduce postoperative oxygenation function in patients who have undergone surgical repair of acute type A aortic dissection. The primary outcomes is the incidence of postoperative hypoxemia (a partial pressure of arterial oxygen to inspiratory oxygen fraction ratio less than 300 mm Hg or a peripheral blood oxygen saturation less than 93% at any concentration of inspiratory oxygen) within 7 days after the surgery.
Who can participate
Age range14 Years – 70 Years
SexALL
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Inclusion criteria
✓. Able to sign Informed Consent and Release of Medical Information Forms;
✓. Age ≥ 14 years and ≤ 70 years old;
✓. Being confirmed the diagnosis by chest computed tomography angiography and receiving the surgical repair of acute type A aortic dissection.
Exclusion criteria
✕. Age \< 14 years or \> 70 years old;
✕. Sepsis before surgery;
✕. Chronic pulmonary disease including lung infection or asthma requiring long-term pharmacotherapy;