CompletedNot Applicable

Ischemic Postconditioning in Carotid Surgery

Serbia40 participantsStarted 2023-09-01

Plain-language summary

Analyzing changes in cerebral oximetry, transcranial Doppler and biomarkers of neuronal ischemic injury and blood-brain barrier integrity assessing the safety and efficacy of ischemic postconditioning in carotid surgery (IPCT).

Who can participate

Age range50 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * unilateral carotid artery stenosis \>90% * bilateral stenosis \>80% * unilateral stenosis \>80% with contralateral occlusion/subocclusion Exclusion Criteria: * urgent carotid endarterectomy * carotid restenosis * "major surgery" in the last 6 months * malignant diseases * previous brain trauma or surgery * epilepsy

What they're measuring

Number of Participants with perioperative stroke

Timeframe: During and 30 days after surgery

Number of Participants with perioperative death

Timeframe: During and 30 days after surgery

Trial details

NCT IDNCT06359756

SponsorInstitute for Cardiovascular Diseases Dedinje

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-01

View on ClinicalTrials.gov More Ischemic Postconditioning trials