The goal of this clinical trial is to learn if using topical tretinoin will help patients with solid tumors who are experiencing an acneiform rash as a side effect of their treatment. Researchers will compare the use of tretinoin on one side of the face to the use of a placebo on the other side of the face to see if there is an impact.
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The maximum difference in modified Investigators Global Assessment (IGA) score between the treated and untreated sides of the face at any assessment.
Timeframe: up to 6 weeks from the initiation of study therapy