Active — Not RecruitingNot Applicable

Re-infusion of Unwashed Shed Blood During Off-pump Surgery

Syria50 participantsStarted 2024-03-27

Plain-language summary

To assess the efficacy and side-effects of re-infusion of unwashed shed blood during off-pump coronary artery surgery using a novel cardiotomy circuit.

Who can participate

Age range40 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All patients undergoing isolated off-pump coronary artery bypass surgery between March 1st, 2024 and March 31st, 2026. Exclusion Criteria: * Missing data. * Patients outside the study period. * Patients under the age of 40 years or over the age of 75 years. * Patients with impaired left ventricular function (EF less the 40%). * Patients with history of renal failure, hepatic failure, CVA, or TIA. * Patients who have not stopped anticoagulants (except aspirin) for 4 days preoperatively. * Emergency operations.

What they're measuring

blood transfusion requirements

Timeframe: up to 5 days post-operatively

inflammatory response

Timeframe: pre-operatively, immediately post-operatively, and 24 hours post-operatively

alveolar/arterial oxygen pressure gradients

Timeframe: pre-, 4 hours post-operatively, and post-extubation

cost-benefit

Timeframe: up to 5 days postoperatively

Neuro-markers

Timeframe: pre-operatively, immediately post-operatively, and 24 hours post-operatively

myocardial marker CK-MB

Timeframe: pre-operatively, immediately post-operatively, and 24 hours post-operatively

myocardial marker troponin-I

Timeframe: pre-operatively, immediately post-operatively, and 24 hours post-operatively

blood loss

Timeframe: up to 24 hours post-operatively

Trial details

NCT IDNCT06358079

SponsorDamascus University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-30

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