This study aims to understand whether changes in a variety of body systems which are seen in adult women with period pain are also seen in adolescents in the first few years of having periods. This information will help to understand 1) how quickly any changes occur, informing clinical practice, and 2) how period pain might lead to other types of chronic pain, potentially allowing development of preventative strategies.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Quantitative Sensory Testing (QST)
Timeframe: days 1-3 (menstrual phase) and days 10-12 (follicular phase) of the menstrual cycle.
Heart rate (HR)
Timeframe: days 1-3 (menstrual phase) and days 10-12 (follicular phase) of the menstrual cycle.
Change in heart rate
Timeframe: days 1-3 (menstrual phase) and days 10-12 (follicular phase) of the menstrual cycle.
Bladder sensitivity to filling
Timeframe: days 1-3 (menstrual phase) and days 10-12 (follicular phase) of the menstrual cycle.
Volume voided at maximum tolerance
Timeframe: days 1-3 (menstrual phase) and days 10-12 (follicular phase) of the menstrual cycle.
Pain Catastrophising: Pain Catastrophising Scale (PCS) (Sullivan)
Timeframe: days 1-3 (menstrual phase) and days 10-12 (follicular phase) of the menstrual cycle.
Area under the curve (AUC) of single day salivary cortisol profile
Timeframe: days 1-3 (menstrual phase) and days 10-12 (follicular phase) of the menstrual cycle.