This 4-week clinical study was designed to examine the antibacterial efficacy of brushing with a 0.454% stannous fluoride toothpaste with potassium nitrate and pyrophosphate compared to a toothpaste containing 0.76% MFP (marketed as Colgate Cavity Protection Toothpaste) in different regions of the mouth (dental plaque, tongue, cheek, gum surface and in saliva) 12 hours post-brushing (overnight) after 2 and 4 weeks of product use.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Whole mouth scores of dental plaque
Timeframe: baseline, 2 week & 4 week
Measurement of total bacterial counts on tongue
Timeframe: baseline, 2 week & 4 week
Measurement of total bacterial counts on cheek
Timeframe: baseline, 2 week & 4 week
Measurement of gingivitis
Timeframe: baseline, 2 week & 4 week
Measurement of total bacterial counts in saliva
Timeframe: baseline, 2 week & 4 week