Neuroimage Genome Study of Neuroplasticity Associated With Microgravity (NCT06350422) | Clinical Trial Compass
UnknownNot Applicable
Neuroimage Genome Study of Neuroplasticity Associated With Microgravity
China26 participantsStarted 2022-01-01
Plain-language summary
This clinical trial investigates the neuroplasticity and cognitive status changes of the human brain in microgravity. To explore the relationship between cognitive status changes and brain functional activities, gray matter and white matter changes under microgravity exposure, screen and identify representative image markers, so as to provide decision-making information for the cognitive status changes of relevant personnel under microgravity environment.
Who can participate
Age range
18 Years – 60 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male aged 18-60 years
* No mental or other neurological disorders, no history of drug or alcohol abuse
* Generally in good condition, no clear major physical diseases, no hearing disorders
* No metal foreign bodies in the body, no contraindications to MRI scanning
* No claustrophobia
* Agree to participate in the clinical study and sign the informed consent
Exclusion Criteria:
* There are electronic implants or metal foreign bodies, such as cardiac pacemakers
* People with aneurysm surgery and intracranial aneurysm clip
* People who have had heart surgery and used artificial heart valves
* Having family planning
* Uncontrolled epilepsy or mental illness, can't cooperate with MRI examination
* Severe claustrophobia, can't cooperate with magnetic resonance examination
* Other circumstances that the clinical trial personnel consider inappropriate to participate in the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Local brain functional activity
Timeframe: 60 days after the Head-Down tilt Bed Rest test
2
Brain functional connectivity
Timeframe: 60 days after the Head-Down tilt Bed Rest test
3
Brain structure - Morphology
Timeframe: 60 days after the Head-Down tilt Bed Rest test
4
Brain fiber bundle and brain Diffusion index
Timeframe: 60 days after the Head-Down tilt Bed Rest test
5
Brain blood flow
Timeframe: 60 days after the Head-Down tilt Bed Rest test
6
Imaging indexes and clinical scale scores
Timeframe: 60 days after the Head-Down tilt Bed Rest test