Early and Late Effects of Nefopam in Multimodal Analgesia After Total Hip Arthroplasty (NEFARTHRO)

Inclusion Criteria: * Patient aged ≥ 18 years, fluent in French. * Planned primary or secondary total hip replacement, regardless of surgical approach or type of prosthesis. * Receiving paracetamol and ketoprofen postoperatively. * Under general anesthesia or spinal anesthesia (without intrathecal morphine). * Participant affiliated to a social security scheme * Participant's free, informed and written consent Exclusion Criteria: * Septic or carcinological surgery * Allergy to paracetamol, nefopam or NSAIDs * Angle-closure glaucoma * Prostate adenoma * history of convulsion * Nocturnal pollakiuria in men with more than two risings per night * Severe hepatic (Child C) or cardiac insufficiency (LVEF \< 30%) * Renal insufficiency with creatinine clearance \< 50 mL/ min according to Cockroft's formula * Active peptic ulcer or history of digestive bleeding or peptic perforation * Patients with opioid treatment for chronic pain other than coxarthrosis (fentanyl, oral morphine \> 50mg/d or equivalent) * Protected patient: safeguard of justice, guardianship or curatorship * Incomprehension or inability to use a numerical rating scale or to self-assess/manage pain * Pregnancy or breast-feeding