The aim of this study was to evaluate the effects of pregnancy on salivary pH, flow rate, caries experience and periodontal status.
The main questions it aims to answer are:
* Does pregnancy affect caries experience and periodontal status?
* Does pregnancy affect salivary pH and flow rate?
* Is there a difference between pregnant and non-pregnant woman with respect to caries experience, periodontal status, salivary pH and flow rate?
* Is there a difference among first, second and third trimester with respect to caries experience, periodontal status, salivary pH and flow rate?
Who can participate
Age range
18 Years – 35 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria for study arms
* Volunteer participants
* Pregnant women aged 18-35 years
* Pregnant woman in different trimesters
* Those who applied to Muğla Sıtkı Koçman University Faculty of Medicine Gynecology and Obstetrics Outpatient Clinic
Inclusion Criteria for control arm
* Volunteer participants
* Non-pregnant women aged 18-35 years
* Those who applied to Muğla Sıtkı Koçman University Faculty of Medicine Gynecology and Obstetrics Outpatient Clinic
Exclusion Criteria:
* Individuals with severe systemic disease
* Individuals who used drugs that directly affect salivary flow rate (e.g., antihypertensive, diuretic, psychotherapeutic, and antiarthritic medications)
* Individuals who used cigarettes or alcohol
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The effects of pregnancy on caries experience
Timeframe: Five minutes after the saliva sample was collected.
2
The effects of pregnancy on periodontal status.
Timeframe: Five minutes after the saliva sample was collected.
3
The effects of pregnancy on salivary pH.
Timeframe: Salivary pH measurements were made within half an hour at the latest after the saliva samples were taken.
4
The effects of pregnancy on salivary flow rate.
Timeframe: Saliva flow rate measurements were made within half an hour at the latest after the saliva samples were taken.