CompletedNot Applicable

Effects of Intact and Disrupted Milk Fat Globule Membrane on Postprandial Metabolic Response to High-fat Dairy in Healthy Individuals

Denmark12 participantsStarted 2024-03-11

Plain-language summary

The aim of the study is to investigate the effects of milk fat globule membrane (MFGM) content and intactness on postprandial metabolic response to a high-fat meal in humans. The investigators hypothesize that MFGM content and intactness alters the postprandial lipid profile and substrate metabolism in healthy individuals after consumption of a high-fat meal.

Who can participate

Age range18 Years – 40 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-40 years * Written and informed consent * HbA1c \< 48 mmol/l Exclusion Criteria: * Medicine with an impact on blood glucose, lipid profile, or blood pressure and birth control pills * BMI \> 30kg/m2 * Affected screening blood sample as evaluated by the clinical responsible investigator * Severe claustrophobia * Lactose intolerance * Doesn't speak and understand Danish * Commitment to special diets

What they're measuring

Difference in postprandial triglycerides measured as area under the curve (AUC).

Timeframe: -60 to 180 minutes after first intervention (first meal), 0-180 minuter after second intervention (second high-fat meal)

Trial details

NCT IDNCT06340412

SponsorUniversity of Aarhus

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-01

View on ClinicalTrials.gov More Postprandial Lipid Metabolism trials