RecruitingNot Applicable

CT-guided Lung Biopsy Risk Optimization Method

Switzerland198 participantsStarted 2025-09-29

Plain-language summary

The purpose of this randomized controlled study is to evaluate the extent to which injection of a small amount of fluid in the pleural cavity at the biopsy site may reduce the risk of pneumothoraces, in addition to patient positioning to allow biopsy in gravity-dependent areas of the lung.

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Ability to provide informed consent (knowledge of project languages), \>18 years. * Indeterminate or suspicious lung lesion unsuitable for transbronchial biopsy or Status after unsuccessful transbronchial biopsy * Indication for biopsy given by referring specialist (in patients). Exclusion Criteria: * Preintervention bleeding into the pleural cavity * More than 1 lesion should be biopsied at the same time * Infiltration of the thoracic wall * Pregnancy

What they're measuring

Number of patients with pneumothorax

Timeframe: Immediate after biopsy, expected to be on average 5 minutes

Trial details

NCT IDNCT06340178

SponsorInsel Gruppe AG, University Hospital Bern

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-04-01

Contact for this trial

Michael Brönnimann, MD

+41316326510 michael.broennimann@insel.ch

View on ClinicalTrials.gov More Pneumothorax trials