CompletedNot Applicable

Systemic Oxidative Stress Score as a Predictor of Gastric Cancer Survival and Recurrence Risk

China3,820 participantsStarted 2022-12-10

Plain-language summary

The Systemic Oxidative Stress Score (SOSS) , a comprehensive score reflecting the oxidative stress conditions in the microenvironment, can independently and effectively predict tumor burden and long-term prognosis in GC patients. Nomograms based on SOSS provide a potential and promising model for risk stratification and guiding the implementation of treatment decisions.

Who can participate

SexALL

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Inclusion Criteria: 1\) gastroscopic histopathological diagnosis of gastric adenocarcinoma; 2) radical gastrectomy for GC; 3) preoperative examination of oxidative indicators including Fbg, CHOL, ALB, TBIL, DBIL, and CR within seven days before surgery; and 4) the tumor did not invade neighboring organs or had no distant metastasis. Exclusion Criteria: 1\) gastroscopic histopathological diagnosis of non-adenocarcinoma, 2) gastric stump cancer, 3) neoadjuvant chemotherapy, 4) other malignant diseases besides GC, 5) incomplete medical records, and 6) patients with GC lost to follow-up.

What they're measuring

5-year OS

Timeframe: 5 years or 60 months

5-year DFS

Timeframe: 5 years or 60 months

Trial details

NCT IDNCT06337279

SponsorFujian Medical University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-08-20

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