CompletedNot Applicable

The Influence of Fit of Underpants Worn on Semen Quality

Thailand120 participantsStarted 2024-03-28

Plain-language summary

The goal of this observational study is to investigate the impact of underpants fit among Thai males attending the Infertility Clinic, whether alone or with their spouses. The main questions it aims to answer are: * Assessing the effect of underpants fit on basic semen parameters and sperm DNA integrity. * Determining the prevalence of preferred type of underpants worn by Thai males. The participants will need to provide informed consent, complete a questionnaire consisting of 28 questions, and provide a semen sample.

Who can participate

Age range

20 Years – 55 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male partner, Thai citizen * Age 20 - 55 years * Participants able and willing to fill in an informed consent form * Participants capable of completing questionnaire form * Semen sample collection after 2-7 days of abstinence * Participants wearing specific type of underpants not less than 8 hours per day Exclusion Criteria: * Any congenital factor (e.g. cystic fibrosis, congenital absence of vas deferens, cryptorchidism) * Any testicular disorder (e.g. varicocele, testicular torsion, testicular trauma) * Any genital tract disorders/ infections (e.g. prostatitis, epididymitis, urogenital tract obstruction) * Severe systemic disorder (e.g. liver cirrhosis, renal failure) * Sexual dysfunction (erectile dysfunction) * Exogenous factors (chemotherapy, medications, radiation) * Any surgery comprising vascularization of testis * Participants wearing both tight and loose-fitted underpants

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.