Adapting Treatment Delivery to Improve Retention in Evidence-Based PTSD Treatment (NCT06335589) | Clinical Trial Compass
CompletedNot Applicable
Adapting Treatment Delivery to Improve Retention in Evidence-Based PTSD Treatment
United States30 participantsStarted 2024-06-24
Plain-language summary
Posttraumatic stress disorder (PTSD) is prevalent among Veterans and effective evidence-based psychotherapies (EBPs) for PTSD have been implemented within the Veterans Health Administration (VHA). However, retention in PTSD EBPs is poor. Premature dropout is associated with worse clinical outcomes and greater healthcare utilization. Delivery of PTSD EBPs in a massed format, typically three or more days per week delivered within a month, have shown promise for increasing retention. The present study is a pilot feasibility and acceptability study comparing massed PTSD treatment to treatment as usual (e.g., typically weekly treatment).
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Veterans aged 18 years or older;
* meets criteria for current PTSD;
* willingness to be randomized to either condition (e.g., EBP-Massed or EBP-TAU);
* decision to receive CPT or PE in a treatment planning session with a Durham Trauma Recovery Program clinic provider;
* ability to provide informed consent
Exclusion Criteria:
* High acute suicide risk;
* active manic symptoms that would likely interfere with treatment;
* active psychotic symptoms that would likely interfere with treatment;
* currently in a concurrent trauma-focused evidence-based treatment for PTSD
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Treatment completion
Timeframe: Immediately after treatment completion or discontinuation (weeks 0-20)
2
Acceptability of Intervention (AIM)
Timeframe: Immediately after treatment completion or discontinuation (weeks 0-20)
3
Client Satisfaction Questionnaire-8 (CSQ-8)
Timeframe: Post-treatment (weeks 0-20)
4
Clinician Administered PTSD Scale for DSM-5 (CAPS-5) Severity Score
Timeframe: Post-treatment (weeks 0-20)
5
Clinician Administered PTSD Scale for DSM-5 (CAPS-5) Severity Score