OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO

Inclusion Criteria: * previously untreated centre-involving DME or ME secondary to RVO with CMT ≥ 300 μm; * pseudophakic eyes or eyes with a transparent lens or only initial sclerosis of the lens, in order to obtain good quality retinal imaging * patient agreement to participate in the study. Exclusion Criteria: * any retinal disease other than DR or RVO; * a positive history of retinal surgery and/or any other macular/retinal treatment (laser, intravitreal injections of anti-VEGF and/or steroids); * cataract surgery within 6 months in the study eye; * refractive error \> +/- 4D; * Advanced glaucoma * neurodegenerative diseases (e.g. multiple sclerosis, Alzheimer disease, Parkinson disease, etc.) * poor quality of OCT and/or OCT-A images due to significant media opacity or poor patient cooperation. * Ocular or periocular infections (including most viral diseases of the cornea and conjunctiva, including active epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, mycobacterial infections, and fungal diseases * Non-intact posterior lens capsule * Hypersensitivity to any component of the product