CompletedNot Applicable

Network Pharmacology Prediction: Mechanism Study of Puerarin in the Treatment of Giant Cell Tumors of Bone

China145 participantsStarted 2012-06-14

Plain-language summary

Based on network pharmacology analysis, this study aims to explore the potential therapeutic targets and molecular mechanisms of puerarin on giant cell tumor of bone (GCTB) genes.

Who can participate

SexALL

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Inclusion criteria

✓. Diagnosed as a patient with giant cell tumor of bone;
✓. Performing surgical treatment in 1st hospital of SYSU;
✓. Having complete clinical registration information;
✓. Preserve surgical or puncture specimens;

Exclusion criteria

✕. Non bone giant cell tumor patients;
✕. No surgical treatment was performed;
✕. Incomplete clinical information registration;
✕. No preserved surgical or puncture specimens.

What they're measuring

P27 expression levels

Timeframe: 2023-05-18 - 2023-08-31

ESR1 expression levels

Timeframe: 2023-05-18 - 2023-08-31

Trial details

NCT IDNCT06331104

SponsorChangye Zou

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-08-31

View on ClinicalTrials.gov More Giant Cell Tumors trials